AI-based personal genome interpretation

Discover what makes you genetically unique.

The most advanced AI tool for personal genome sequencing data. Enhance your genome with personalized variant reports and data-driven suggestions to improve your health. Just $39.

75,000+ genetic variants|AI-powered, always current|Privacy by default

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Crimson Iris

Your most unique genetic variants

Variant	Impact	Tags
RPL3L c.1167+1G>A	4	heartLoF
APOE p.Cys130Arg	2	brainmissense
HFE p.His63Asp	1	bloodmissense

Personal Genomic Report

All findings refer to one copy (heterozygous) of a DNA change unless stated otherwise.

Category	Takeaway	Next steps
Iron & blood	Changes in HFE, TFRC, TMPRSS6 that can affect body iron and red-cell size.	Blood tests (CBC, ferritin, transferrin sat.) at your next physical.

How it works

Provide your genome file

Crimson Iris works best with whole-genome or whole-exome sequencing data.

Review your report

We provide a curated list of the most unique variants found in your genome, and specific actions you can take to learn more.

Subscribe to stay up-to-date

By default your data will be deleted after 30 days, or subscribe to get notifications when science changes.

The science

We have designed the Crimson Iris model to answer the question: 'What are the genetic variants that are most likely to contribute to my unique traits and the unique traits in my family?'. The model incorporates two key pieces of information — the frequency of a genetic variant, and the strength of its impact on a wide variety of diseases and traits.

We have curated a set of tens of thousands of genetic variants that are most likely to be relevant to your health and traits, and for each of them we compute a 'uniqueness score' that takes into account these two pieces of data. The data sources include results from ClinVar, the UK Biobank, the All of Us Research Program and gnomAD, among others.

Once we have sorted variants by uniqueness, we use language models like chatGPT to generate text summaries for a report that provides actionable next steps based on the set of variants found in your genome.

About

Crimson Iris is run by Dr. Joe Pickrell, a geneticist and entrepreneur with a passion for making genome sequencing data more accessible and interpretable.

The goal of Crimson Iris is to help individuals understand what makes them genetically unique, and to synthesize the complex science into clear and actionable next steps.